Sir Thomas Denton (1574-1633) was an English landowner and politician who sat in the House of Commons between 1604 and 1629.

Denton was the eldest son of Alexander Denton of Hillesden and his wife Mary Martin, daughter of Sir Roger Martin, Lord Mayor of London.

Following his marriage in 1594, he lived at Stowe, Buckinghamshire, and in 1601, he was High Sheriff of the county.

In 1628 he was elected MP for Buckingham again and sat until 1629 when King Charles decided to rule without parliament for eleven years.

His daughter Margaret married Sir Edmund Verney.