He was the eldest son of William Handcock and his wife Abigail, daughter of Sir Thomas Stanley and sister of Thomas Stanley.
[2] His younger brother was Sir William Handcock, Recorder of Dublin.
[3] In 1692, Handcock entered the Irish House of Commons, representing Lanesborough until 1699.
[1] On 5 July 1677, he married Dorothy Green, and had, by her, four sons and four daughters.
[3] His oldest son William sat also in the Parliament of Ireland.