[2] By 1860, Wynne had returned to his Irish roots in the west of Ireland and on 4 August 1860 he married Ellen Semple in the Roman Catholic church in Castlebar, county Mayo.

Ellen died in 1862, her death attributed to complications in giving birth to their only son John William Wynne (12 July 1861–).

Possibly unusually for the time, in June 1887, Wynne advertised a situation vacant for a "a Lady having good knowledge of Retouching and Spotting.

"[4] In late September 1884, Wynne was advertising "splendid photos" of the wreck of the gunboat HMS Wasp, which had sunk on reefs near Tory Island, off the north-west coast of County Donegal, with the death of 52 crew members.

[1] One of his daughters, Mary Hannon (née Wynne) (1864–1925), established a photographic studio in Loughrea, Galway in the 1890s and was also a member of the Irish Literary Society.