A member of the Republican Party from Chester County, Eyre had a long career in appointed state offices before running for senate.

In July, Eyre joined the James A. Beaver gubernatorial administration as an employee of the Pennsylvania Department of Internal Affairs.

Governor Robert E. Pattison, a Democrat, took office in 1891, and opted not to retain Eyre, so he joined Matthew Quay's U.S. Senate campaign.

When Republicans regained the governorship under Daniel H. Hastings in 1895, Eyre returned to the Pennsylvania Department of Internal Affairs as deputy secretary.

Eventually, Eyre served Chester County (District 19) in the Pennsylvania Senate from 1919 to 1926, including two years as president pro tempore.