William Carey Crane, an eminent theologian, said his sermons "did not sway men so much by touching appeals as by presenting the truth to them with irresistible power."

[2] Unusually for the time, he supported the higher education of women, and called for the convention to establish "a female seminary of high order."

Although a native Pennsylvanian, Meredith adapted to his adopted region as a slave owner for most of his adult life, a fact he never revealed in his public writing.

In his pamphlet Meredith argued "that slaveholding is, per se, wholly inoffensive; that the relation of master and slave is as accordant with the general precepts of the gospel, as that of parent and child, or of husband and wife; and that, therefore, all charges of a criminal nature founded on this relation, and alleged against Southern Christians, are unreasonable and unjust.”[6] Beyond slavery Meredith also weighed in on "Campbellism", which threatened to cause a split in the Baptist movement, temperance, and the troubled relationship with the Triennial Convention.

Meredith often published multi-issue expositions of key doctrines or defenses of traditional evangelical theological convictions, always providing a rigorously orthodox view.