Born in 1759 at Currigg in the chapelry of Raughtonhead, Cumberland, he was the fourth son of John Sanderson (1723–1776), by his wife Sarah Scott of Caldbeck.
He returned to his mother's house at Sebergham, and lived in complete seclusion, but occasionally met, at a spot overlooking the River Caldew, Josiah Relph, the Cumbrian poet.
[1] Sanderson had some success as a poet, and legacies from relatives; he gave up teaching and retired to Kirklinton, nine miles north-east of Carlisle, where he boarded with a farmer, and spent the remainder of his life as a writer.
[1] In 1807 Sanderson issued a Companion to the Lakes, a compilation from Thomas Pennant, William Gilpin, and Arthur Young, supplemented by personal knowledge.
He defended the literary style of David Hume against Gilbert Wakefield, in two essays in the Monthly Magazine, and contributed a memoir of Boucher to the Carlisle Patriot for July 1824.