He had to leave school and help his father in his business when 13; about 18 months later he was apprenticed for a short time to a glover in The Poultry, in the City of London.
He became a popular preacher in the neighbourhood of London, and in December 1808 preached at Lady Huntingdon's chapel at Brighton.
On 10 January 1809 he addressed large congregation from Rowland Hill's pulpit in Surrey Chapel, Southwark.
[1] Having visited Liverpool in the summer of 1810, Spencer on 26 September accepted an offer of the pastorate of Newington chapel there.
An elegy by James Montgomery was appended to the Memoirs of Spencer written by his successor at Liverpool, Thomas Raffles.