He was appointed archbishop of the Archdiocese of Miami by Pope Benedict XVI on April 20, 2010, and was installed on June 1, 2010.

[5][9] During his twelve years at the seminary, he was a self-described "very liberal seminarian," questioning Catholic teaching on clerical celibacy and the ordination of women.

[5] His views eventually became more conservative through his experience working with Cuban immigrants and reading about communism in Poland and Cuba.

[10] Wenski then began his studies in philosophy and theology at St. Vincent de Paul Minor Seminary in Boynton Beach.

[5] After returning to Miami in 1979, Wenski was appointed to a Haitian apostolate operating out of the Cathedral of Saint Mary.

[7] He also served concurrently as pastor of three Haitian parishes in the archdiocese: Notre-Dame d'Haiti in Miami,[14] Divine Mercy in Fort Lauderdale, and St. Joseph in Pompano Beach.

[5] He also befriended Jean-Bertrand Aristide, a now laicized priest who later became the first democratically elected President of Haiti,[5][15] Wenski celebrated the weekly Mass in English for shut-ins at WPLG, the local ABC affiliate, from 1992 to 1997, and directed the Ministry to Non-Hispanic Ethnic Groups.

Later in 1996, he spearheaded a relief operation that delivered over 150,000 pounds (68,000 kg) of food to Caritas Cuba for distribution to people left homeless by Hurricane Lili.

[20] At the time of his appointment to Miami in 2010, he was leading the diocese through the early stages of both a $150 million capital campaign and an extensive renovation of St. James Cathedral in Orlando[21] In October 2007, Wenski was selected to serve on the board of directors of the Florida Specialty Crop Foundation, a non-profit public charity that assists specialty crop producers and their stakeholders.

[23] At the Mass, he denounced Obama for his "rather extremist views on abortion" and said that Notre Dame's "actions suggest that, unlike a Carrie Prejean, it lacks the courage of its convictions.

[4] Following his appointment, he said he was "humbled by the Holy Father's confidence in me and aware of my own limitations and shortcomings..."[32] He succeeded Archbishop Favalora.

[2] At the end of June, he received the pallium, a vestment worn by metropolitan bishops, from Benedict XVI at St. Peter's Basilica.

This came a week after then Vice President Joe Biden officiated a wedding for two male White House staff members.