Thomas Wetmore (September 20, 1767 – March 22, 1828) was a lawyer and political figure in New Brunswick.
He came to New Brunswick after the American Revolution in 1783, first settling at Carleton (later Saint John) and then Gagetown.
He was named clerk for the Inferior Court of Common Pleas and registrar of deeds for Carleton County.
In 1809, Wetmore was elected to the Legislative Assembly of New Brunswick for St. John County; he did not run for reelection in 1816.
In the same year, he was named Attorney General for the colony and served in the post until his death on his estate near Fredericton at the age of 60.