He was ordained priest at Rome in 1695, and went afterwards to the college of St. Thomas Aquinas at Louvain, where he became successively professor of philosophy, theology, and sacred scripture.
For nine years he laboured on the English mission, sometimes in London, but generally in Yorkshire and Lancashire.
in 1718, was elected prior of Bornhem for the fifth time in 1725, and was again instituted provincial on 4 January 1725−6.
Subsequently he became chaplain at Middleton Hall, the residence of Ralph Brandling, in the parish of Rothwell, near Leeds.
His works are: Worthington was the fourth son of Thomas Worthington of Blainsco in the parish of Standish, near Wigan, Lancashire, by his wife Jane, eldest daughter of John Plompton of Plompton, Yorkshire, was born on 23 November 1671 Cooper, Thompson (1900).