Thomas Zacharia (born 1957 in Kerala, India) is an Indian-born American computer scientist.

He has contributed to research in computational materials science, particularly on Marangoni Effect in solidification processes.

[4] Zacharia was previously deputy director for science and technology at Oak Ridge National Laboratory[5] and a professor at the University of Tennessee.

[6] On June 1, 2017, UT-Battelle named Zacharia as ORNL's new laboratory director, succeeding Thom Mason.

[7] During his tenure, he launched the UT-Oak Ridge Innovation Institute, the Stable Isotope Production and Research Center, and the Quantum Science Center, among other initiatives.