Thompsonville is a census-designated place (CDP) in the town of Enfield in Hartford County, Connecticut, United States.

Orrin Thompson, from whom the community takes its name, built a dam across Freshwater Brook in 1828 and opened the first carpet mill in 1829.

Initially its product was largely flat-woven ingrain carpeting, an inexpensive type of carpeting, but over time it added more expensive weaves, such as three-ply ingrain and loop brussels.

[2] Carpeting continued to be manufactured in Thompsonville until 1971, by which time most production had shifted to the southern United States.

U.S. Route 5 (Enfield Street) is the main road through the village, leading north to Longmeadow, Massachusetts, and into Springfield, and south through East and South Windsor to East Hartford.