Thompsonville is a village in Cave Township, Franklin County, Illinois, United States.

[citation needed] Thompsonville is located in southeastern Franklin County at 37°54′59″N 88°45′42″W / 37.91639°N 88.76167°W / 37.91639; -88.76167 (37.916443, -88.761564).

[4] Illinois Route 34 passes through the village, leading northwest 10 miles (16 km) to Benton, the county seat, and southeast 21 miles (34 km) to Harrisburg.

There were 261 housing units at an average density of 127.50 per square mile (49.23/km2).

45.91% of all households were made up of individuals, and 31.82% had someone living alone who was 65 years of age or older.