[1] Mild-mannered Erwin Trowbridge, bored with his suburban New Jersey life with his wife and brother-in-law and frustrated by his low-paying job writing greeting card verses, decides to declare his independence by skipping work and spending the day in a local saloon.

When they discover Erwin has an almost supernatural ability to go through a racing form and pick the winners, they persuade him to join them at a New York City hotel and regularly give them tips.

Complications arise when Erwin begins to miss his wife and job and his cronies insist he put some money on a horse himself, despite his claim he will lose his power if he places a bet.

Directed by co-author George Abbott, with a set design by Boris Aronson, the opening night cast starred Sam Levene as Patsy, Shirley Booth as Mabel, William Lynn as Erwin Trowbridge and Teddy Hart as Frankie; Garson Kanin performed the featured role of Al, and later became assistant to director and co-author, George Abbott.

Since the John Cecil Holm and George Abbott script includes references not generally known in Britain, the theatrical program had a glossary so the audience would understand the expressions used in the play, which may have been a reason for its shorter run versus the original Broadway production.

[9] Directed by Stanley Prager and choreographed by Onna White, the Broadway musical opened at the Eugene O'Neill Theatre on October 12, 1961 and closed December 9, 1961 after running for 68 performances and one preview.

[10] A 1936 film adaptation released by Warner Bros. was produced and directed by Mervyn LeRoy and starred Frank McHugh, Joan Blondell, Guy Kibbee and Sam Levene who reprised the role of Patsy he created in the original Broadway production.

[11] A 1957 German language film adaptation, Drei Mann auf einem Pferd, starred Walter Giller and Nadja Tiller.

In 1989, a film version, titled Let It Ride with the same basic plot—though purportedly based on a novel— was adapted for an American produced screen comedy starring Richard Dreyfuss.

[17] In 1936, Milton Bradley introduced an Art Deco inspired Three Men On A Horse board game based on the 1936 Warners Bros.