[3] The film's screenplay was written by Adele Comandini and Austin Parker, and is about three sisters who travel to New York City to prevent their father from remarrying.

It began an eight-year span of successful Deanna Durbin musicals and spawned two sequels, Three Smart Girls Grow Up and Hers to Hold.

[5] By August Dante had dropped out and the three girls were to be played by Durbin, Nan Grey and Barbara Read.

[6] Ray Milland was a last-minute replacement for Louis Hayward, who was originally cast, but fell ill shortly of pleurisy four days into filming.

[9] Three Smart Girls received Academy Award nominations for Best Picture, Best Sound (Homer G. Tasker), and Best Original Story.