Threlfalls Brewery is a Grade II listed building on Cook Street, Salford, England, built in 1896 to the design of W.A.

It was completely self-contained, even down to its own telephone switchboard, and when the staff were transferred from Ardwick it was under the pretence that all their jobs would continue and that Chesters would maintain its own identity.

At Crook Street the two sets of offices were gradually merged and staffing reduced, as had always been expected.

Whitbread took over the group including the Moorhouse's soft drinks company in 1967 and the Salford site became surplus to requirements in 1999.

Whitbread closed the company's head office, brewery and bottling plant in Trueman Street Liverpool in the early 1980s.