Thrombotic storm

A very small number of people who develop blood clots have a more serious and often life-threatening condition, known as thrombotic storm (TS).

TS may be associated with an existing condition or situation that predisposes a person to blood clots, such as injury, infection, or pregnancy.

While the mechanism or pathogenesis is not completely understood, mostly due to its rarity, the medical community has developed a new interest in learning more about this syndrome.

Hypercoagulable states can be an inherited or acquired risk factor that then serves as a trigger to initiate clot formation.

Preliminary diagnosis consists of evidence documented with proper imaging studies such as CT scan, MRI, or echocardiography, which demonstrate a thromboembolic occlusion in the veins and/or arteries.

Vascular occlusions mentioned must include at least two of the clinic events: In addition to the previously noted vascular occlusions, development of different thromboembolic manifestations simultaneously or within one or two weeks must occur, and the patient must have an underlying inherited or acquired hypercoagulable state (other than antiphospholipid syndrome).