It premiered on March 29, 2008 at the Ted Mann Concert Hall in Minneapolis, and was videotaped for subsequent broadcast on PBS and a DVD released in June 2008.

Through A Glass, Darkly follows a night in the lives of three young gay men: Sebastian, a burned-out Wall Street stockbroker addicted to crystal meth; Billy, a young man he picks up in a bar and turns on to the drug before seducing him; and Zack, Sebastian's boyfriend, who waits at home wondering what has become of his partner.

In June 2009, the Gay Men's Chorus of Washington, D.C., performed the East Coast premier at Lisner Auditorium, featuring Tim Tourbin as Sebastian, Philip Lee "Peelee" Clark as Billy, and Justin Bank as Zack.

In April 2010, the Philadelphia Gay Men's Chorus performed the show at the Arden Theatre, featuring Matt Geyer as Sebastian, Justin Scott as Billy, and Albert Fernandez as Zack.

In June 2010, the New York City Gay Men's Chorus performed it as the centerpiece of its concert, High, featuring Timothy Morrell as Sebastian, Mark Silverstone as Billy, and Michael Osso as Zack.