Blondeau started modeling at a very young age, and in 2006, was elected "Most Beautiful Girl in The World" by Vogue Enfants.
She is the daughter of Patrick Blondeau, a footballer, and Véronika Loubry [fr], an actress and television presenter.
[2] She starred alongside Zendaya, Lucky Blue Smith and Presley Gerber in the Dolce & Gabbana millennial-themed spring/summer 2017 campaign.
[18][19][non-primary source needed] In December 2018, Thylane placed first in the annual "Independent Critics List of the 100 Most Beautiful Faces of 2018".
[21] Blondeau made her acting debut playing the role of Gabriele in the film Belle & Sebastian: The Adventure Continues (2015).