1500)[1] and Ranuccio Farnese (died 1529), the two undisputed legitimate children of Paul III, who were born before his election as pope in 1534.
On 20 November 1551 he was promoted to the Order of Cardinal Priests, but he was allowed to continue to hold the deaconry of S. Agata as though it were a titulus, pro illa vice (on that one occasion) until 1562.
[11] He was appointed Administrator of the Diocese of Sessa Aurunca (1565 – 27 June 1566) during the vacancy caused by the death of Bishop Galeazzo Florimonte.
[14][15] He also commissioned a palace in Bolsena that bears his name, Palazzo di Tiberio Crispo (also known as the Palazzo Crispo Marsciano or Palazzo Rondanini alla Rotonda), which was designed by Antonio da Sangallo the Younger circa 1543;[16] after the death of Sangallo in 1546, Raffaello da Montelupo was called in to finish the palace, which remained incomplete, however, after the deaths of both Crispo and Raffaello in 1566.
[17] Historical research indicates that Crispo also likely owned the "Palazzo Nobile" in Rome, a palace originally commissioned for Thomas Cardinal Wolsey circa 1507 before passing to the Aldobrandini family; Crispo likely commissioned the 400 square metres of frescos in the palace which celebrate the life of Paul III.