Promos for the show suggested that Big Brother would be different this year, and phrases such as "Assume Nothing, Expect Anything", "Let's Play" and "Think Again" were used throughout the series, especially during Opening Night.

[1] On Opening Night, it was revealed that A$5,000 would be subtracted from the $1 million prize money every time the housemates broke a rule.

It was revealed that twins would be entering the House, regularly changing places without the other housemates knowing—this was a twist first used on the fifth American series of Big Brother.

As a result, both Logans were able to continue living in the House, but would be treated as a single person in matters such as evictions and nominations.

Before this, Constance, Dean and Nelson were all evicted to the Punishment Room; and were told their fate by Big Brother.

A public vote was held, that was started on Day 9 and was closed during the show, minutes before two of these housemates who had broken the rules were evicted.

They both had separate eviction interviews with Gretel, and were both told that, because they had deceived Big Brother, they would receive no prizes.

[3] Dean was safe, but Big Brother still punished him by banning him from nominations and by putting him up for the public vote next week.

was a live show broadcast during Day 25, where replacement housemates Rachael and Vesna were introduced to the public and put in the House.

With David and Greg both living in the House as a single housemate, the twins were put up for eviction as two separate people.

Greg, Melanie, Tim and Vesna all competed against a team of ex-housemates to try to win a A$20,000 addition to the prize fund.

Bree Amer and Ryan Fitzgerald, Friday Night Live co-presenters and former Big Brother 2004 housemates, participated in one of the games, each as an additional member of one of the teams.

Logan councillor and future Queensland MP Aidan McLindon jumped on the set as Gretel Killeen prepared to announce the winner, and was later fined $250.