Pioneered by his grandparents Martin and Clara in 1926, the farm operation includes raising corn, cattle, wheat, milo, and soybeans.

He attended elementary and high school in Fowler, where he was a Farm Bureau Youth Leader, a member of St. Anthony's Parish, and active in both 4-H and Future Farmers of America.

Huelskamp was endorsed by the Club for Growth, Mike Huckabee,[10][11] Conservative Leadership PAC, Concerned Women for America Legislative Action Committee,[2] Ron Paul and Ken Blackwell.

[20] On February 16, 2012, during a contentious three-hour House Budget Committee hearing with Treasury Secretary Timothy Geithner, Huelskamp warned of what he considered to be the looming threat of an economic crisis similar to the one then taking place in Europe.

Huelskamp accused Geithner and the entire Obama administration of failing to correct the U.S.'s debt crisis, which he believed would lead the country down the same path.

[25] At a luncheon organized by The Heritage Foundation in the immediate wake of the removal, Huelskamp said, "It's petty, it's vindictive, and if you have any conservative principles you will be punished for articulating those.

"[26] He joined Justin Amash of Michigan and David Schweikert of Arizona in a letter to Speaker of the House John Boehner, demanding to know why they had lost their "plum" committee posts.

[27] Politico quoted a spokesperson for Republican Congressman Lynn Westmoreland of Georgia as explaining that Huelskamp, Amash and Schweikert were removed for "their inability to work with other members."

The three were described by Politico and its sourcing of Huelskamp's other colleagues as "jerks" who "made life harder for other Republicans by taking whacks at them in public for supporting the team".

[28][29]: p.2 On January 3, 2013, Huelskamp appeared to be counting votes as part of an effort to unseat House Speaker John Boehner when the 113th Congress convened.

[35] His PAC was responsible for sending misleading texts the day before the 2022 Kansas Primary, indicating that a Yes vote protected abortion choice, although the reverse was true.