The music video contains footage from live shows (parts of which are slowed down), depictions of Egyptian hieroglyphs, a short animated sequence, and clips shot at a studio.

The video ends with a view of the night sky with stars forming the name of the band.

The Seattle band Pearl Jam covered Timeless Melody in their Binaural Tour on 6/4/2000 when they played at The Manchester Evening News Arena, Manchester, England.

Pearl Jam went on to play the song several more times on the tour, often as a duet with Supergrass frontman Gaz Coombes.

Pearl Jam have also performed the song with Death Cab for Cutie in 2004.