Predating Britpop by four years,[3] the band's self-titled album was named one of the 40 greatest one-album wonders by Rolling Stone, with the magazine stating, "Whether about heroin or just unrequited love, the La's single 'There She Goes' off their self-titled debut has endured as a founding piece of Britpop's foundation.

"There She Goes" has gained a reputation for being about the use of heroin, possibly as a result of the lines: "There she goes again... racing through my brain... pulsing through my vein... no one else can heal my pain".

"[9] However, in the book In Search of The La's: A Secret Liverpool (2003) by MW Macefield, ex-La's guitarist Paul Hemmings denied the rumour.

[12] Andrews' production of the song was remixed by Steve Lillywhite in 1990 for inclusion on their debut album The La's.

The first video, released in 1988 and directed by Jeff Baynes, was an amateur-style recorded on a camcorder, and was shot in the English countryside and in the band's hometown of Liverpool.

Recorded on professional cameras and shot in Los Angeles, California, it was the band's first video to feature the new line-up, which consisted of lead guitarist Peter Camell and drummer Neil Mavers (Camel's younger brother).

The second video shows them performing in the streets and neighboring towns of Los Angeles, as well as in front of the Los Angeles skyline, evidenced by the presence of the U.S. Bank Tower, while being interspliced with footage of a young woman, before ending with a shot of her face.

It has appeared on several film soundtracks, including The Parent Trap; Fever Pitch; Girl, Interrupted; Cold Case; The Adventures of Pete and Pete; Snow Day; and So I Married an Axe Murderer (where both the original and The Boo Radleys version appear).

Sixpence None the Richer's version of the song was used in Family Guy and the commercials for birth-control company Ortho Tri-Cyclen Lo from 2004 to 2005.

[63] The song was also used for the opening montage of the first episode, "Spring", of Channel 4's drama series This Is England '90, which also featured outgoing Prime Minister Margaret Thatcher's resignation speech.

[64] The song was used frequently for slow-motion scenes with Nori Sterling (Reylynn Caster) in the U.S. TV series Me, Myself & I.

The BBC comedy drama There She Goes was named after the song, as the show’s creator Shaun Pye listened to it whilst writing the first script.