Tirupati–Sainagar Shirdi Express is an Express train belonging to Indian Railways which connects Tirupati in Andhra Pradesh with Shirdi in Maharashtra.

It operates as train number 17417 from Tirupati to Sainagar Shirdi and as train number 17418 in the reverse direction, serving the states of Andhra Pradesh, Karnataka, Telangana & Maharashtra .

The train covers the distance of 1,436 km (892 mi) in 29 hours 15 mins approximately at a speed of (48 km/h (30 mph)).

As with most train services in India, coach composition may be amended at the discretion of Indian Railways depending on demand.

This train rake share with 07605 Tirupati-Akola and 07606 Akola-Tirupati Superfast Special Express As this route is fully electrified, train is hauled by WAP-4 locomotive of Bhusawal from Tirupati to Sainagar Shirdi and vice-versa.