[1] A myocardial infarction induces tissue remodeling of the heart in a three-phase process: inflammation, proliferation, and maturation.
In the proliferation phase, inflammatory cells die by apoptosis, being replaced by myofibroblasts which produce large amounts of collagen.
[2] By contrast, aerobic exercise can produce beneficial cardiac tissue remodeling in those suffering from left ventricular hypertrophy.
[3] Programmed cellular senescence contributes to beneficial tissue remodeling during embryonic development of the fetus.
[5] Vascular remodeling refers to a compensatory change in blood vessel walls due to plaque growth.