Tixkokob (Spanish pronunciation: [tiʃ.koˈkoβ], meaning place of poisonous snakes in Mayan) is a town in the Mexican state of Yucatán, located in the north central part of the state.

It is the seat of Tixkokob Municipality and is located about 24 miles east of the city of Mérida.

Prior to the Spanish conquest of Yucatán, this area belonged to the chieftainship of Ceh-Pech.

There is no record of the founding date of the population and its earliest reference is from the year 1549.

This article about a location in the Mexican state of Yucatán is a stub.