Tlaxco (Nahuatl: "place of the ball game"[6]) is a town and its surrounding municipality in the Mexican state of Tlaxcala.

From east to west on its northern side, it borders the municipalities of Ixtacamaxtitlán and Chignahuapan in Puebla, and Almoloya and Apan in Hidalgo.

[6] The highest point in the municipality is the Cerro Peñas Coloradas located at 19°39′55″N 98°03′11″W / 19.6653°N 98.0531°W / 19.6653; -98.0531 with an elevation of 3,360 metres (11,020 ft) above sea level.

[7] Although minor settlements have been found in the Tlaxco area dating back to the Texoloc phase or Middle Formative period, sedentary settlement of the area properly began in the Tezoquipan phase or Late Formative period by proto-Teotihuacan peoples who share elements of the Tezoquipan culture.

From 650 to 850 AD, northern Tlaxcala experienced a period of political instability known as the Acopinalco Complex, during which many different cultural groups competed for control over the area.

[6] The municipal government comprises a president, a councillor (Spanish: síndico), and seven trustees (regidores) elected by proportional representation.