These hosts include tobacco, zucchini, cucumbers, carrots, French bean, tomatoes, potatoes, and tulips.

In infected plants, abnormal coloring or necrotic tissue in the leaves may occur and roots may have lesions.

Prior to planting, one can reduce risk of this disease by investigating the history of their soil for past presence of TNV or of its fungal host vector Olpidium brassicae.

[3] While tobacco necrosis virus can infect many crops, it has a small economic impact relative to other plant pathogens.

[5][6] For example, TNV has a high level of resistance to heat and chemical agents, as well as to degradation due to aging.