It was loosely based on the format of the popular American television show, Live with Regis and Kelly.

Although the filming pattern varied, for much of the show's run, Monday's, Tuesday's, and Wednesday's programmes were recorded 'as live' very shortly before start of transmission (typically being recorded about half an hour prior), while Thursday's and Friday's episodes were pre-recorded in a separate block on Wednesdays.

The series pulled in extremely high ratings for its daytime slot, and as a result at one stage, the show was given the green light for an evening version to be made.

Other guest presenters include Dale Winton of Supermarket Sweep, Bradley Walsh of The Chase and the first-ever Countdown host Richard Whiteley OBE also covered for Des on occasion.

O'Grady had requested their use in this capacity as he felt indebted to the pair for playing a role in him being awarded his own show.