Todd Duffee (born December 6, 1985) is an American mixed martial artist who competes in the Heavyweight division of Konfrontacja Sztuk Walki (KSW).

Duffee was born in Evansville, Indiana, but grew up in Raleigh, Illinois, and Eldorado as the third son of a coal miner father and nurse mother.

Duffee played many sports growing up, including baseball, football, track, bull riding, soccer, and basketball.

Duffee then moved to Atlanta, Georgia when he was 18 years old and continued boxing, before watching a UFC event and shifting his training to mixed martial arts.

[9] Duffee set the record for the fastest KO in UFC heavyweight history (0:07) after flooring Hague with a stiff jab and rendering him unconscious with follow-up ground and pound.

Duffee was expected to face Paul Buentello at UFC 107[11][12] but pulled out due to a back injury.

[22] Duffee said after the fight that he respected Overeem's ability but felt that if he had sufficient time to train and prepare that it would have been a completely different outcome.

[27] He faced fellow UFC veteran Neil Grove on the SFL's second show held on April 7, 2012.

Duffee was appealing to promoters on Twitter for fights in both MMA and Professional Boxing but none came to fruition by the time of SFL's next event.

[33] After the De Fries fight it emerged that Duffee had fought with an undisclosed injury sustained during his training camp and would be ruled out for much of 2013.

However, 3 weeks into his return to the gym, after waking up with severe pains and numbness in his arm Duffee was diagnosed with an unknown affliction which was later revealed to be Parsonage–Turner syndrome.

After battling the infection, Duffee relocated to Las Vegas in order to rehabilitate and continue training at the UFC Performance Institute.

[41] After a four-year hiatus, Duffee returned to face Jeff Hughes on September 14, 2019, at UFC Fight Night 158.

[42] The bout ended in the first round as a No Contest due to an accidental eye poke that rendered Duffee unable to continue.

[43] In May 2021, Duffee returned to training after successfully rehabbing further shoulder and knee surgeries, as well as a positive COVID-19 diagnosis.

[47] Duffee was scheduled to make his bare-knuckle boxing debut for Bare Knuckle Fighting Championship against Ben Rothwell at BKFC 56 on December 2, 2023.

[50] In 2011 Duffee made his film debut in the Michael Jai White-produced Never Back Down 2: The Beatdown, portraying Tim Newhouse, a talented MMA fighter who lives in relative poverty and has to deal with losing his father.