[2] Since about 1656 Mendoza held the charges of alcalde mayor of the region and Lieutenant General of the Rio Abajo zone.
In June of that year, Tome III was ordered to form an troop against the Apaches who were attacking Socorro and Senecú.
For the last decade, Tomé III continued to participate in political and military functions in the province.
In 1681, Tomé Domínguez III de Mendoza, at sixty-one years old, died from gout and a stomach disease.
[2] Mendoza married twice: his first marriage was to Catalina López Mederos, with whom he had 6 children: Tome III, Antonio, Juana, Francisco (who died in the war against the Puebloans), Juan and Diego (both were injured in the same war) Domínguez de Mendoza.
[2] About 1659, Governor Bernardo López de Mendizábal gave Mendoza an encomienda to the south of Isleta.
In Isleta, the Dominguez family settled to the west of El Cerro de Tomé,[3] near Tome Hill (next to Rio Grande).