Thomas L. Hughes (January 28, 1884 – November 1, 1961) was an American right-handed baseball pitcher for the New York Highlanders (1906–07 and 1909–1910) and Boston Braves (1914–1918).

On August 30, 1910, Hughes took a no-hitter into the 10th inning, before allowing a single to Cleveland's Harry Niles.

[2][3] On June 16, 1916, Hughes successfully completed a no-hitter, against the Pittsburgh Pirates at Braves Field; he struck out future Hall-of-Famer Honus Wagner for the final out.

[4] Hughes' accomplishments include being the Braves franchise career leader in WHIP (1.022) and hits allowed per nine innings (6.77).

In nine seasons, Hughes had a 56–39 win–loss record, while appearing in 160 games and pitching 863 innings; he had a 2.56 ERA and 476 strikeouts.