[1] He previously served as chairman and CEO of his business, The Wolf Organization, and later as secretary of the Pennsylvania Department of Revenue from April 2007 to November 2008.

During the administration of Governor Robert P. Casey, Wolf served on an economic development board and on the Pennsylvania Legislative Commission on Urban Schools.

[17] After selling his company to a private equity firm in 2006, Wolf was nominated by then-governor Ed Rendell in January 2007 to be the secretary of revenue of Pennsylvania.

He was the third person to announce candidacy, after John Hanger of the Pennsylvania Department of Environmental Protection and Max Meyers, a minister from Cumberland County, but at least four others were expected to join the race.

[26] In late April and early May, Wolf faced attacks from fellow candidate Rob McCord over his association with controversial former York, Pennsylvania, mayor Charlie Robertson.

Insiders have attributed this phenomenon to Regional Field Director Brendan Murray and his extensive relationship network in north-central Pennsylvania.

[42] Shortly after being sworn in, Wolf signed two executive orders banning gifts to state employees and requiring a bidding process for outside legal contracts.

[43] Wolf also restored a ban on hydraulic fracturing, or "fracking", in state parks[44] and placed a moratorium on the death penalty in Pennsylvania.

[49] Wolf argued the budget was not balanced, disputing Republicans' claim that it would provide increased funding in certain areas without raising taxes.

[citation needed] On November 30, 2016, Wolf announced the awarding of "It's On Us PA" grants of $1 million to 36 post-secondary schools in the state to combat sexual violence on their campuses.

Programs considered for funding included but were not limited to those that enhanced awareness of available resources as well as the rights of students and, most importantly, to increase mechanisms for anonymous reporting.

Such a declaration lets Pennsylvania officials "override any current rules or regulations they perceive as hampering the state's ability to address the opioid epidemic".

[59] On November 3, 2022, signed 66 new laws sent to him by the legislature addressing a range of issues, including new initiatives designed to curb the opioid epidemic along with clean energy tax credits[60] and cracking down on turnpike toll scofflaws.

[61] Wolf signed into law bills that legalized medical marijuana in Pennsylvania, reformed pensions, and expanded the number of offenses former criminal defendants could get sealed, among other legislation.

[69] On June 23, State Representative Daryl Metcalfe and 24 co-sponsors introduced five articles of impeachment in House Resolution 915 against Wolf based on charges that the mandates he imposed amid the pandemic damaged Pennsylvania's economy and exceeded his authority by unilaterally and unlawfully.

[72] On September 14, 2020, District Court Judge William S. Stickman IV ruled that the restrictions Wolf imposed during the pandemic were unconstitutional, violating the right to freedom of assembly guaranteed by the First Amendment.

Both passed, with publications declaring the measures victorious with 52% of the vote on May 19, making Pennsylvania the first state to approve a curb on a governor's emergency powers since the start of the COVID-19 pandemic.

[77][78] In March 2021, Wolf announced the state would start rolling out the one-dose Janssen COVID-19 vaccine in order to get students back into the classroom for in-person instruction.

[79] In August, Wolf announced that students, teachers, and staff in all public and private K-12 schools and child care facilities would be required to wear masks amid a rise in cases caused by the SARS-CoV-2 Delta variant.