The series is somewhat similar to the "older" version of the original theatricals, partly akin to being produced by creators William Hanna and Joseph Barbera, founders of Hanna-Barbera and former MGM cartoon studio staff.

The two will usually end up clashing with McWolf, the before-unnamed villainous wolf from Avery shorts that, envious of their success, will use any dirty trick against them to win, but inevitably fails.

The beautiful Miss Vavoom (Red in Avery shorts) is another possible source of conflict between the two, as both of them have a crush on her and she, or a kiss from her, is often the prize of some sort of competition.

Parent company Turner Broadcasting System would buy the Hanna-Barbera studios in late 1991 starting with the third season.

In 1994, Fox canceled the series and ended its run on Fox Kids on September 4, 1994, but it soon began airing in reruns on Cartoon Network (which Turner launched to showcase its large animation library, including the original Tom and Jerry) in 1995, and ended in 2007[citation needed] when the show was removed from the Cartoon Network schedule and moved to its sister channel Boomerang.

However, it made a brief return to the Cartoon Network airwaves on June 4, 2023, during a marathon consisting on other Tom and Jerry shows.

[4] In 2010, the episode Flippin' Fido was included in the Deluxe Anniversary Collection DVD set with the original opening and closing titles restored, different from TV airing versions.

In the United Kingdom, Season One was released as 2 separate DVDs on August 12, 2013, under the titles Baby Tom and Jerry, as part of WB's Big Faces range.

[citation needed] In Mexico, Editorial Vid made a comic book based on Tom & Jerry Kids in 1990.