Fisher is best remembered for her 1959 song "The Big Hurt", written by her manager Wayne Shanklin.
[4][5] DJ Dick Biondi on WKBW in Buffalo, New York, would introduce the record as "Toni Fisher's weird one".
Disc jockey Wink Martindale commented that the record label billed the singer as "Miss Toni Fisher" because of her powerful voice, which is consistently audible over the phasing, the instruments, and the background noise, to confirm to the listener that the singer is indeed a woman.
[6] "The Big Hurt" was later covered by Wes Montgomery, Del Shannon, Scott Walker, Vikki Carr, Nick Cave, and others.
Fisher died in Salt Lake City, Utah, on January 11, 1999, of a heart attack at age 74.