Buzbee appeared on the cover of The New York Times magazine in November 2010 regarding his role in the litigation against BP following the Deepwater Horizon oil spill in the Gulf of Mexico.

[6] As of April 6, 2021, Buzbee represents at least twenty-one clients alleging sexual misconduct against NFL Quarterback Deshaun Watson.

[7][8][9] In 2021, Buzbee filed a $750 million lawsuit against rapper Travis Scott on behalf of 120 victims who died or were injured during the Astroworld Festival crowd crush.

[16] Buzbee was the lead trial attorney for Rebecca Grossman, who was convicted of second-degree murder in Los Angeles in 2024 after a 2020 hit-and-run that killed two brothers.

[23] According to Buzbee, Roc Nation paid off some of his former cilents to file bogus lawsuits, while Quinn Emanuel orchestrated the scheme.

[23] In 2002, Buzbee unsuccessfully ran for the 24th district of the Texas State House as a Democrat, losing to Republican Larry Taylor by 17 points.

Later on, following the release of the Access Hollywood tape, Buzbee disavowed Trump and stated his intention to write in veteran Dan Moran for president.

[45][46] The following year, Buzbee garnered public attention for parking a fully operational World War II-era Sherman M4A4 tank, named "Cheyenne," on Houston's River Oaks Boulevard.

This incident led to a series of parking citations and a conflict with the River Oaks Property Owners' Association, resulting in the tank's eventual relocation to Texarkana.

[48] Buzbee was accused of giving a sexually transmitted infection to a woman in a lawsuit filed in the New York Supreme Court in December 2024.

She alleged that Buzbee asked her to not disclose testing positive after a doctor confirmed she had a venereal disease and offered her legal advice as compensation.