He eventually received a Bachelor of Science degree in commercial art from the University of Santo Tomas in the Philippines.

With writer John Albano, he co-created the long-running western character Jonah Hex,[8] and with Sheldon Mayer the first Black Orchid.

[9] DeZuniga served as an introduction to what would be a 1970s influx of Filipino artists to American comics, prompting Orlando and DC publisher Carmine Infantino to visit the Philippines in 1971 to scout talent.

[10] Among the artists found there who would soon become mainstays of both DC and Marvel Comics were Alfredo Alcala, Alex Niño, Nestor Redondo, and Gerry Talaoc.

[13] Around this time, DeZuniga formed Action Art Studio, which was a group of New York-based Filipino komiks artists who inked various Marvel Comics titles under the collective pseudonym of "The Tribe."

[7] DeZuniga later became a videogame conceptual designer, spending a decade with the United States and Japan divisions of Sega.

His legacy will be seen and felt in the multitude of fans he leaves behind and the incredible body of work of which he remained justifiably proud to his final days.