[1] Before becoming a Nation of Islam minister, he worked as the real estate executive of a fast-food chain and was an Eastern Air Lines manager in Atlanta.

[1] His term got off to a rocky start, his congregation being forcibly evicted from the building they occupied in 1996, for failing to fulfill the conditions of their lease-to-buy contract.

[4] Muhammad was credited for bringing a more collaborative style to the organization in Los Angeles, favoring dialogue between the community and police forces.

[2] Since 2012, Muhammad and Reverend Alfreddie Johnson host Peace Rides to promote non-violence in Los Angeles County, such as in Compton.

[14] Drawing on parallels from the Bible, Muhammad has been preaching that pharmaceutical companies and the United States Government are using vaccines to specifically harm African American and Latin male children.

[16][17] The March 2021 hour-long video elaborates on Muhammad's conspiracy theories, claiming that the United States government seeks to harm ethnic minorities with COVID vaccines, along with rehashed anti-vaccination stories about autism, Bill Gates and the Centers for Disease Control.

Several African American leaders testified on that occasion that contrary to Muhammad, they supported California's efforts to have a greater number of children vaccinated.

[23][8] In 2016, Muhammad joined Andrew Wakefield and Del Bigtree for the promotion tour of the anti-vaccination Vaxxed, using the Nation of Islam to bring people to thirty screenings.