Topawa (O'odham: name Ḍo Bawui translates as "Gathering Tepary Beans") is a census-designated place and unincorporated community in Pima County, Arizona, United States.

Topawa is located on the Tohono O'odham Nation reservation, 7.5 miles (12.1 km) south-southeast of Sells.

[3] At the 2020 census there were 315 people, 101 households, and 70 families living in the CDP.

[7] Within the community is also located the San Solano Missions, the parish houses Catholic priests who serve the reservation.

Less than two miles from Topawa, the Tohono O'odham Nation also operates their Himdag Ki: Cultural Center and Museum.