Alabi developed an interest in music at a young age, participating in her church choir and singing during school events.

[10] Tope Alabi began her career in the Nigerian entertainment industry in the 1990s, working as an actress and singer for the theater group Jesters International.

[12] Her ability to craft spiritually uplifting music, often blending Yoruba proverbs and Christian teachings, earned her recognition within the industry.

[13][14] In 2000, Alabi released her debut album, Ore ti o Common (Uncommon Favor), which gained significant popularity and established her as a leading gospel artist in Nigeria.

[25][26] In 2021, Tope Alabi faced criticism for her comments regarding a popular gospel song, "Oniduro Mi," by fellow artist Adeyinka Alaseyori.

Alabi's remarks were perceived as critical of the song's lyrics, leading to a public backlash from fans and supporters of both artists.