It forms part of the Turin–Genoa main line, and is also a stop on three secondary railways, which link Turin with Pinerolo, Cuneo and Savona, respectively.

Lingotto station on the Metropolitana di Torino (Turin Metro) was opened nearby on March 6, 2011.

The assumed reduction in future capacity of Torino Porta Nuova may further increase the station's importance.

On 20 November 2007, the architect Massimiliano Fuksas submitted a preliminary project commissioned by the Piedmont Region for the redevelopment of the Via Nizza area, which previously housed the now demolished factories of Fiat Aviazione.

The subsequently approved plan included construction of a new Piedmont Region Headquarters within a 686 ft skyscraper, currently set to open in 2022.