The group was founded by five graduates from Prague's Institute of Chemical Technology[1] in early 2007, and the same year they played their first live show.

Toxique's debut single, "Two Sides", took part in national selection for Czech's entry in the Eurovision Song Contest 2008.

[4] In 2009, they released singles "Honey" and "eBay", which did not match the success of their debut song.

[7][8] In November, the band toured the UK with Polish singer Kayah as part of O2's Your Country live concert series.

In 2013, the band's lead vocalist Klára Vytisková embarked on a solo career and released singles "Country Girl" and "Survival".