[1] Established in 2014 and published by Duke University Press, it is the first non-medical journal about transgender studies.

[1] While co-editing a special transgender studies issue of Women's Studies Quarterly in 2008, Stryker and Currah realized the need for a publication dedicated to the topic,[6] when they received over 200 submissions for the special issue but were only able to publish 12.

[7] They received more than US$10,000 in donations in the first five days; by the end of the campaign, the journal had nearly $25,000 in crowdfunded capital.

[8][9] The title of the first issue, "Postposttranssexual", comes from Sandy Stone's 1987 article "The Empire Strikes Back: A Posttranssexual Manifesto", which has been called the start of transgender studies.

Past issue themes have included surgery, pedagogy, archives, trans/feminisms, and blackness.