He played college basketball for the UMass Minutemen, Texas Longhorns, West Virginia Mountaineers, and Kentucky Wildcats.
[1] As a senior, he averaged 16.6 points, 13.5 rebounds, 3.6 assists and 2.6 blocks per game, leading his team to a 39–2 record and the National Prep Championship quarterfinals.
[6] In his final game of the season, on March 7, he posted a season-high 34 points and 12 rebounds in a 64–63 loss to Rhode Island.
On February 15, 2022, the program announced that Mitchell would take an indefinite leave of absence from the team; he missed the rest of the season.
After one season playing for West Virginia, Mitchell entered the transfer portal following the resignation of head coach Bob Huggins in June 2023.