[3][4][5] The native regions where Trema lamarckianum occurs include Florida in North America, West Indies, Bermuda, Grand Cayman and the Bahamas.

[6] Trema lamarckianum is considered a pioneer species and can grow in a wide range of disturbed areas, even those whose ground is predominately sedimentary or igneous rocks.

The areas in Puerto Rico where this species grows has an annual rainfall between 1200 and 3000 mm.

They can be found growing on road cuts, unsteady slopes and landslidesareas, disrupting work at these sites.

Approximately, 60–120 days after sowing in commercial potting mix, 38 percent of seeds have germinated.

Reproduction can be enhanced by disturbing the soil close to seed-bearing plants before the seasonal rain begins.