He later spent the 2017 season on the Atlanta Falcons practice squad before joining the Arizona Hotshots of the Alliance of American Football in 2018, until the league ceased operations in April 2019.

[6] He was named MVP of the 2014 Sugar Bowl when he helped lead Oklahoma to a 45–31 upset of two-time reigning national champion Alabama.

[8] On December 11, 2015, it was announced that Knight had obtained a full release from his scholarship and would explore his options to transfer to another school.

After showcasing his physical ability at the combine, multiple teams approached him about the possibilities of converting to wide receiver or safety.

[17] On March 30, 2017, Knight participated at Texas A&M's pro day, along with Jermaine Eluemunor, Justin Evans, Myles Garrett, Daeshon Hall, Ricky Seals-Jones, Josh Reynolds, and seven others.

At the conclusion of the pre-draft process, he was projected to be a seventh round pick or a priority undrafted free agent.

[19] On April 29, 2017, the Arizona Cardinals signed Knight to a three-year, $1.66 million contract after he went undrafted in the 2017 NFL draft.

[22][23] Throughout training camp, he competed with veteran Blaine Gabbert for the job as the third-string quarterback behind Carson Palmer and Drew Stanton.

In addition to his relief duties, Knight served as a jammer on special teams, lining up for the punt return unit.