The Trifinio Biosphere Reserve is a protected area in Guatemala, located where the borders of Guatemala, El Salvador, and Honduras meet (thus the prefix tri in its name).

[1] It protects the Guatemalan portion of the Montecristo massif and its cloud forests, and is the Guatemalan portion of the Trifinio Fraternidad Transboundary Biosphere Reserve, which spans the three countries' borders.

The biosphere reserve was created to protect the Montecristo cloud forest and its rare flora and fauna.

[2] The dense cloud forest of oak and laurel trees, which grow up to 30 meters high, houses rare wildlife species like the two-fingered anteater, striped owls, toucans, agoutis, pumas, and spider monkeys.

[3] El Salvador's Montecristo National Park was created in 2008.