Trine Skei Grande (born 2 October 1969) is a Norwegian politician who served as the leader of the Liberal Party of Norway from 2010 to 2020.

Prior to entering politics full-time she worked as a part-time journalist, a high school teacher and as a lecturer at Nord-Trøndelag University College.

Grande was a member of the Liberal Party central board in 1999–2000, and was deputy leader from 2000 until 2010.

She is a member of the Norwegian Association for Women's Rights and has highlighted the legacy of her predecessor as Liberal Party leader Eva Kolstad.

On 11 March 2020, she announced her intention to resign as party leader, minister and not stand for re-election in 2021.