Tripleurospermum is a genus in the chamomile tribe within the sunflower family.

[2][3] Mayweed is a common name for plants in this genus.

[4] Most of the species are from Europe and temperate Asia although a few are from North America and North Africa.

[5][6][7] Plants typically have lobed leaves that are composed of one to three opposite pairs cut almost to the leaf mid rib: they have indehiscent one-celled fruits that have 3-ribs and two resinous glands at the base, Matricaria species are distinguished from these species by lacking fruits with 3-ribs and the two glands.

[8] There are approximately 40 species recognised in the genus Tripleurospermum:[9] The genus is closely related to Heteromera, Matricaria, and Pyrethrum.